Acquired resistance is a common and difficult problem in the treatment of Cancer. Often Tumours initially respond to treatment, only for them over time to become resistant and stop responding to treatment. The Resistant Cancer Cell Line Collection is a set of more than 1300 cancer cell lines that is used to model acquired resistance in cancer. this website provides access to drug sensitivity data for cell lines within the RCCL. Data provided are primarily IC50 values for both the drug a cell line has been adapted to and other drugs
This website offers a powerful resource for obtaining and analysing resistance and cross resistance data from the RCCL database. There are multiple ways to search the RCCL, they are displayed below and further information is available from the Help page