Resistant Cancer Cell Line Collection

Jindrich Cinatl
Dr Petra Joh-Forschungshaus
Frankfurter Stiftung für krebskranke Kinder
Frankfurt am Main, Germany

Wass-Michaelis Research Group
School of Biosciences
University of Kent
Kent, UK
Investigate Data for a single Drug: topotecan
Topotecan - Drug Information
Basic information about the drug is displayed below. This has been extracted from the Wikipedia entry for the drug -
Drug Structure
Clinical data
Trade names Hycamtin
AHFS/ Monograph
MedlinePlus a610007
US: D (Evidence of risk)
Routes of
Intravenousoral (capsules)
ATC code L01XX17 (WHO)
Pharmacokinetic data
Bioavailability 31.4 %
Protein binding 35%
Biological half-life 2–3 hours
Excretion Renal
CAS Number 123948-87-8
PubChem CID 60700
DrugBank DB01030
ChemSpider 54705
KEGG D08618
Topotecan Drug sensitivity Data
The table and barchart show all drug sensitivity data for topotecan

In the bar chart resistant sub-lines are shown in a lighter shade of the parental cell line