Resistant Cancer Cell Line Collection
Jindrich Cinatl
Dr Petra Joh-Forschungshaus
Frankfurter Stiftung für krebskranke Kinder
Frankfurt am Main, Germany
Wass-Michaelis Research Group
School of Biosciences
University of Kent
Kent, UK
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Investigate Data for a single Drug: topotecan
Topotecan - Drug Information
Basic information about the drug is displayed below. This has been extracted from the Wikipedia entry for the drug -
https://en.wikipedia.org/wiki/Topotecan
Drug Structure
Clinical data
Trade names
Hycamtin
AHFS
/
Drugs.com
Monograph
MedlinePlus
a610007
Pregnancy
category
US
:
D
(Evidence of risk)
Routes of
administration
Intravenous
oral (
capsules
)
ATC code
L01XX17
(
WHO
)
Pharmacokinetic
data
Bioavailability
31.4 %
Protein binding
35%
Biological half-life
2–3 hours
Excretion
Renal
Identifiers
CAS Number
123948-87-8
PubChem
CID
60700
DrugBank
DB01030
ChemSpider
54705
KEGG
D08618
ChEMBL
CHEMBL84
Topotecan Drug sensitivity Data
The table and barchart show all drug sensitivity data for topotecan
In the bar chart resistant sub-lines are shown in a lighter shade of the parental cell line