Resistant Cancer Cell Line Collection

Jindrich Cinatl
Dr Petra Joh-Forschungshaus
Frankfurter Stiftung für krebskranke Kinder
Frankfurt am Main, Germany

Wass-Michaelis Research Group
School of Biosciences
University of Kent
Kent, UK
Investigate Data for a single Drug: topotecan
Topotecan - Drug Information
Basic information about the drug is displayed below. This has been extracted from the Wikipedia entry for the drug - https://en.wikipedia.org/wiki/Topotecan
Drug Structure
Topotecan.svg
Clinical data
Trade names Hycamtin
AHFS/Drugs.com Monograph
MedlinePlus a610007
Pregnancy
category
US: D (Evidence of risk)
Routes of
administration
Intravenousoral (capsules)
ATC code L01XX17 (WHO)
Pharmacokinetic data
Bioavailability 31.4 %
Protein binding 35%
Biological half-life 2–3 hours
Excretion Renal
Identifiers
CAS Number 123948-87-8
PubChem CID 60700
DrugBank DB01030
ChemSpider 54705
KEGG D08618
ChEMBL CHEMBL84
Topotecan Drug sensitivity Data
The table and barchart show all drug sensitivity data for topotecan

In the bar chart resistant sub-lines are shown in a lighter shade of the parental cell line