Resistant Cancer Cell Line Collection

Jindrich Cinatl
Dr Petra Joh-Forschungshaus
Frankfurter Stiftung für krebskranke Kinder
Frankfurt am Main, Germany

Wass-Michaelis Research Group
School of Biosciences
University of Kent
Kent, UK
Investigate Data for a single Drug: temozolomide
Temozolomide - Drug Information
Basic information about the drug is displayed below. This has been extracted from the Wikipedia entry for the drug - https://en.wikipedia.org/wiki/Temozolomide
Drug Structure
Temozolomide structure.svg
Temozolomide-3D-spacefill.png
Clinical data
Trade names Temodar, Temodal, Temcad
AHFS/Drugs.com Monograph
MedlinePlus a601250
Pregnancy
category
US: D (Evidence of risk)
Routes of
administration
Oral, intravenous
ATC code L01AX03 (WHO)
Pharmacokinetic data
Protein binding 15%
Biological half-life 1.8 hours
Identifiers
Synonyms cisplatinum, platamin, neoplatin, cismaplat, cis-diamminedichloridoplatinum(II) (CDDP)
CAS Number 85622-93-1
PubChem CID 5394
DrugBank DB00853
ChemSpider 5201
KEGG D06067
ChEBI CHEBI:72564
ChEMBL CHEMBL810
Temozolomide Drug sensitivity Data
The table and barchart show all drug sensitivity data for temozolomide

In the bar chart resistant sub-lines are shown in a lighter shade of the parental cell line