Resistant Cancer Cell Line Collection

Jindrich Cinatl
Dr Petra Joh-Forschungshaus
Frankfurter Stiftung für krebskranke Kinder
Frankfurt am Main, Germany

Wass-Michaelis Research Group
School of Biosciences
University of Kent
Kent, UK
Investigate Data for a single Drug: paclitaxel
Paclitaxel - Drug Information
Basic information about the drug is displayed below. This has been extracted from the Wikipedia entry for the drug - https://en.wikipedia.org/wiki/Paclitaxel
Drug Structure
Taxol.svg
Taxol(Paclitaxel)3D.png
Clinical data
Trade names Taxol, others
AHFS/Drugs.com Monograph
Pregnancy
category
US: D (Evidence of risk)
Routes of
administration
Intravenous
ATC code L01CD03 (WHO)
Pharmacokinetic data
Bioavailability 6.5% (by mouth)
Protein binding 89 to 98%
Biological half-life 5.8 hours
Excretion Fecal and urinary
Identifiers
CAS Number 33069-62-4
PubChem CID 36314
DrugBank DB01229
ChemSpider 10368587
KEGG D00491
ChEBI CHEBI:45863
ChEMBL CHEMBL428647
PDB ligand CPT (PDBe, RCSB PDB)
Paclitaxel Drug sensitivity Data
The table and barchart show all drug sensitivity data for paclitaxel

In the bar chart resistant sub-lines are shown in a lighter shade of the parental cell line