Resistant Cancer Cell Line Collection

Jindrich Cinatl
Dr Petra Joh-Forschungshaus
Frankfurter Stiftung für krebskranke Kinder
Frankfurt am Main, Germany

Wass-Michaelis Research Group
School of Biosciences
University of Kent
Kent, UK
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Investigate Data for a single Drug: irinotecan
Irinotecan - Drug Information
Basic information about the drug is displayed below. This has been extracted from the Wikipedia entry for the drug - https://en.wikipedia.org/wiki/Irinotecan
Drug Structure
Irinotecan.svg
Irinotecan ball-and-stick.png
Clinical data
Trade names Camptosar (US), Campto (EU), Onivyde
AHFS/Drugs.com Monograph
MedlinePlus a608043
Pregnancy
category		 US: D (Evidence of risk)
Routes of
administration		 Intravenous
ATC code L01XX19 (WHO)
Pharmacokinetic data
Bioavailability NA
Protein binding > 95%
Biological half-life 6 to 12 hourss
Excretion Biliary and Renal
Identifiers
Synonyms cisplatinum, platamin, neoplatin, cismaplat, cis-diamminedichloridoplatinum(II) (CDDP)
CAS Number 97682-44-5
PubChem CID 60838
DrugBank DB00762
ChemSpider 54825
KEGG D08086
ChEBI CHEBI:80630
ChEMBL CHEMBL481
Irinotecan Drug sensitivity Data
The table and barchart show all drug sensitivity data for irinotecan

In the bar chart resistant sub-lines are shown in a lighter shade of the parental cell line