Resistant Cancer Cell Line Collection

Jindrich Cinatl
Dr Petra Joh-Forschungshaus
Frankfurter Stiftung für krebskranke Kinder
Frankfurt am Main, Germany

Wass-Michaelis Research Group
School of Biosciences
University of Kent
Kent, UK
Investigate Data for a single Drug: erlotinib
Erlotinib - Drug Information
Basic information about the drug is displayed below. This has been extracted from the Wikipedia entry for the drug - https://en.wikipedia.org/wiki/Erlotinib
Drug Structure
Erlotinib Structural Formulae.png
Erlotinib-1m17-3D-balls.png
Clinical data
Trade names Tarceva
AHFS/Drugs.com Monograph
MedlinePlus a605008
Pregnancy
category
US: D (Evidence of risk)
Routes of
administration
Oral tablets
ATC code L01XE03 (WHO)
Pharmacokinetic data
Bioavailability 59%
Protein binding 95%
Biological half-life 36.2 hours
Excretion Renal (urine)
Identifiers
Synonyms cisplatinum, platamin, neoplatin, cismaplat, cis-diamminedichloridoplatinum(II) (CDDP)
CAS Number 183321-74-6
PubChem CID 176870
DrugBank DB00530
ChemSpider 154044
KEGG D07907
ChEBI CHEBI:114785
ChEMBL CHEMBL553
Erlotinib Drug sensitivity Data
The table and barchart show all drug sensitivity data for erlotinib

In the bar chart resistant sub-lines are shown in a lighter shade of the parental cell line