Resistant Cancer Cell Line Collection

Jindrich Cinatl
Dr Petra Joh-Forschungshaus
Frankfurter Stiftung für krebskranke Kinder
Frankfurt am Main, Germany

Wass-Michaelis Research Group
School of Biosciences
University of Kent
Kent, UK
Investigate Data for a single Drug: doxorubicin
Doxorubicin - Drug Information
Basic information about the drug is displayed below. This has been extracted from the Wikipedia entry for the drug - https://en.wikipedia.org/wiki/Doxorubicin
Drug Structure
Doxorubicin2DCSD.svg
Doxorubicin 3D ball.png
Clinical data
Trade names Adriamycin, Doxil, Caelyx, Myocet, others
AHFS/Drugs.com Monograph
MedlinePlus a682221
Pregnancy
category
US: D (Evidence of risk)
Routes of
administration
Intravenous,
intravesical
ATC code L01DB01 (WHO)
Pharmacokinetic data
Bioavailability 5% (by mouth)
Protein binding 75%
Biological half-life Triphasic; 12 minutes, 3.3 hours, 30 hours. Mean: 1-3 hours
Excretion Urine (5-12%), faeces (40-50%)
Identifiers
Synonyms cisplatinum, platamin, neoplatin, cismaplat, cis-diamminedichloridoplatinum(II) (CDDP)
CAS Number 23214-92-8
PubChem CID 31703
DrugBank DB00997
ChemSpider 29400
KEGG D03899
ChEBI CHEBI:28748
ChEMBL CHEMBL53463
Doxorubicin Drug sensitivity Data
The table and barchart show all drug sensitivity data for doxorubicin

In the bar chart resistant sub-lines are shown in a lighter shade of the parental cell line