Resistant Cancer Cell Line Collection

Jindrich Cinatl
Dr Petra Joh-Forschungshaus
Frankfurter Stiftung für krebskranke Kinder
Frankfurt am Main, Germany

Wass-Michaelis Research Group
School of Biosciences
University of Kent
Kent, UK
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Investigate Data for a single Drug: dacarbazine
Dacarbazine - Drug Information
Basic information about the drug is displayed below. This has been extracted from the Wikipedia entry for the drug - https://en.wikipedia.org/wiki/Dacarbazine
Drug Structure
Dacarbazine.svg
Clinical data
Trade names DTIC-Dome, others
AHFS/Drugs.com Monograph
MedlinePlus a682750
Pregnancy
category		 US: C (Risk not ruled out)
Routes of
administration		 Intravenous
ATC code L01AX04 (WHO)
Pharmacokinetic data
Bioavailability 100% (IV)
Biological half-life 5 hours
Excretion Renal (40% as unchanged dacarbazine)
Identifiers
CAS Number 4342-03-4
PubChem CID 2942
DrugBank DB00851
ChemSpider 10481959
KEGG C06936
ChEBI CHEBI:4305
ChEMBL CHEMBL476
Dacarbazine Drug sensitivity Data
The table and barchart show all drug sensitivity data for dacarbazine

In the bar chart resistant sub-lines are shown in a lighter shade of the parental cell line

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