Resistant Cancer Cell Line Collection

Jindrich Cinatl
Dr Petra Joh-Forschungshaus
Frankfurter Stiftung für krebskranke Kinder
Frankfurt am Main, Germany

Wass-Michaelis Research Group
School of Biosciences
University of Kent
Kent, UK
Investigate Data for a single Drug: cytarabine
Cytarabine - Drug Information
Basic information about the drug is displayed below. This has been extracted from the Wikipedia entry for the drug - https://en.wikipedia.org/wiki/Cytarabine
Drug Structure
Cytarabin.svg
Cytarabine ball-and-stick.png
Clinical data
Trade names Cytosar-U, Depocyt, others
AHFS/Drugs.com Monograph
MedlinePlus a682222
Pregnancy
category
US: D (Evidence of risk)
Routes of
administration
injectable (intravenous injection or infusion, intrathecal, or subcutaneously)
ATC code L01BC01 (WHO)
Pharmacokinetic data
Bioavailability 20% by mouth
Protein binding 13%
Biological half-life biphasic: 10 min, 1–3 hr
Excretion Renal
Identifiers
Synonyms cisplatinum, platamin, neoplatin, cismaplat, cis-diamminedichloridoplatinum(II) (CDDP)
CAS Number 147-94-4<
PubChem CID 6253
DrugBank DB00987
ChemSpider 6017
KEGG D00168
ChEBI CHEBI:28680
ChEMBL CHEMBL803
PDB ligand CPT (PDBe, RCSB PDB)
Cytarabine Drug sensitivity Data
The table and barchart show all drug sensitivity data for cytarabine

In the bar chart resistant sub-lines are shown in a lighter shade of the parental cell line