Resistant Cancer Cell Line Collection

Jindrich Cinatl
Dr Petra Joh-Forschungshaus
Frankfurter Stiftung für krebskranke Kinder
Frankfurt am Main, Germany

Wass-Michaelis Research Group
School of Biosciences
University of Kent
Kent, UK
Investigate Data for a single Drug: cisplatin
Cisplatin - Drug Information
Basic information about the drug is displayed below. This has been extracted from the Wikipedia entry for the drug - https://en.wikipedia.org/wiki/Cisplatin
Drug Structure
Cisplatin-stereo.svg
Cisplatin-3D-vdW.png
Clinical data
Trade names Platinol, others
AHFS/Drugs.com Monograph
MedlinePlus a684036
Pregnancy
category
US: D (Evidence of risk)
Routes of
administration
Intravenous
ATC code L01XA01 (WHO)
Pharmacokinetic data
Bioavailability 100% (IV)
Protein binding > 95%
Biological half-life 30–100 hours
Excretion Renal
Identifiers
Synonyms cisplatinum, platamin, neoplatin, cismaplat, cis-diamminedichloridoplatinum(II) (CDDP)
CAS Number 15663-27-1
PubChem CID 84691
DrugBank DB00515
ChemSpider 76401
KEGG D00275
ChEBI CHEBI:27899
ChEMBL CHEMBL2068237
PDB ligand CPT (PDBe, RCSB PDB)
Cisplatin Drug sensitivity Data
The table and barchart show all drug sensitivity data for cisplatin

In the bar chart resistant sub-lines are shown in a lighter shade of the parental cell line